The Cardiovascular Research Foundation (CRF), has announced the 2025 Scientific Excellence Top 10 (SET-10), honoring leading global institutions whose pioneering research in interventional cardiology will take center stage at TCT® 2025 (Transcatheter Cardiovascular Therapeutics®), CRF’s annual scientific symposium, to be held in San Francisco from October 25 to 28, 2025. Launched in 2023, the SET-10 honors institutions whose groundbreaking research is shaping the future ofcardiovascular careand advancing the science that saves lives. This year’s rankings spotlight 33 institutions whose research will be featured at TCT® 2025 reflecting exceptional contributions across a wide range of categories — from basic science to late-breaking clinical research — both in the United States and around the world. The SET-10 rankings are based on cumulative scores from submissions to TCT 2025 and celebrate institutions at the forefront of innovation in interventional cardiovascular medicine. Rankings are presented across six key categories: Global, United States, Non-U.S., Coronary, Structural, and Late-Breaking Clinical Research. Here is the global ranking of top 10 global leaders in cardiovascular research. “We’re proud to honor the institutions driving global progress in interventional cardiovascular medicine through the third annual CRF® SET-10 rankings,” said Juan F. Granada, MD, President and CEO of CRF® and TCT® Program Director. “The research featured at TCT 2025 reflects the tremendous momentum in our field and the relentless pursuit of better patient outcomes. These institutions are not only fueling innovation — they’re shaping the future of cardiovascular care and inspiring the next generation of scientific discovery.”