One-step adhesive system tied to development of greatest number of new white spot lesions and mineral loss suggests a new study published in The Angle Orthodontist

A study was done to compare the development of white spot lesions (WSLs) during fixed orthodontic therapy among a conventional three-step bonding system, a self-etching primer bonding system, and a one-step adhesive bonding system.
Seventy-five patients were randomly allocated into three groups (group 1, conventional bonding system, n = 25; group 2, self-etch primer, n = 25; group 3, primer mixed with adhesive composite, n = 25). Quantitative light-induced fluorescence (QLF) was used to assess WSL parameters. Images were captured and then analyzed before treatment and at 2 months and 4 months after bond up. Lesion area (pixels), mean fluorescence loss (ΔF), and the number of newly developed WSLs were compared within and among the three groups. The significance level was P ≤ .05.

Results
The mean increase in lesion area was 31.3 ± 2.8 pixels, 38.4 ± 4.3 pixels, and 119.5 ± 5.3 pixels for groups 1, 2, and 3, respectively (P ≤ .001). For ΔF, the loss was 3.3% ± 0.3%, 4.4% ± 0.2%, and 6.6% ± 0.2% for groups 1, 2, and 3, respectively. These changes were significantly different (P ≤ .01 to P ≤ .001). The incidence of newly developed lesions was 9.5 WSLs in group 1, 10 WSLs in group 2, and 15.9 WSLs in group 3.
The lack of primer contributed to the development of a larger number of and more severe white spot lesions (WSLs).
Reference:
Ola G. Abu Horan, Susan N. Al-Khateeb; Comparison of three orthodontic bonding systems in white spot lesion development: a randomized clinical trial. Angle Orthod 2023; doi:https://doi.org/10.2319/111422-781.1
Keywords:
One-step, adhesive system, tied, development, greatest, number, new white, spot, lesions, mineral loss, The Angle Orthodontist, Self-etch primer, One-step adhesive, Conventional bonding system, WSLs, QLF