October 23, 2025

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Family History of Fracture Significantly Raises Future Fracture Risk: Meta-Analysis Finds

UK: A large-scale meta-analysis published inOsteoporosis Internationalreinforces the role of family fracture history as a critical predictor of futurefracture risk, independent ofbone mineral density (BMD). The study, led by Eugene V. McCloskey and colleagues from the Centre for Metabolic Bone Diseases, University of Sheffield, highlights the potential need to update fracture risk assessment models, including the widely used FRAX tool, to reflect these findings.

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