APAP-MAD therapy combo significantly increased compliance with APAP therapy among patients with moderate-to-severe OSA suggests a recent study published in the European Journal of Dentistry.
The purpose of this pilot study was to determine whether compliance to auto-adjusting positive airway pressure (APAP) improves with the addition of a mandibular advancement device (MAD). Secondary outcome measures included were APAP pressure, subjective daytime sleepiness, apnea–hypopnea index (AHI), and mask leaks.
Participants included were diagnosed with moderate-to-severe obstructive sleep apnea (OSA) and became noncompliant to prescribed APAP. Thirteen participants with a mean age of 61.6 years were recruited for this study. All participants were given a MAD to use with their APAP. Parameters measured included APAP pressure, AHI, mask leak reported via ResMed AirViewTM software, and self-reported daytime sleepiness (Epworth Sleepiness Scale [ESS]). A paired two-sample for mean t-test was performed to determine significance.
Results:
• The mean difference of pre- and postintervention APAP compliance was 23.1%, which was statistically significant (p = 0.015).
• The mean APAP air pressures were unchanged.
• The difference between pre- and postintervention mean ESS scores was 1.4 and was statistically significant (p = 0.027).
• The mean difference between pre- and postintervention AHI values and mask leak showed no significant difference.
This study showed that combination of APAP-MAD therapy, for patients with moderate-to-severe OSA who were noncompliant to APAP use, significantly increased compliance with APAP therapy, and significantly decreased the daytime sleepiness of participants.
Reference:
Thyagaseely Sheela Premaraj , Jacob Stadiem , Shyamaly Arya Premaraj , Charles R. Davies , Matthew Dennis , John J. Harrington. Continuous Positive Airway Pressure-Mandibular Advancement Device Combination Therapy for Moderate-to-Severe Obstructive Sleep Apnea: A Preliminary Study. CC BY 4.0 · Eur J Dent 2022; 16(04): 749-755. DOI: 10.1055/s-0040-1719220
Keywords:
APAP-MAD, therapy, combo ,significantly, increased, compliance, APAP, therapy, patients moderate-to-severe OSA, Thyagaseely Sheela Premaraj , Jacob Stadiem , Shyamaly Arya Premaraj , Charles R. Davies , Matthew Dennis , John J. Harrington