In a recent study , published in BMJ, Journal of Cardiothoracic Surgery, several risk factors associated with postoperative delirium after cardiac surgery have been identified. " Utilizing the information may allow us to identifying patients at high risk of developing postoperative delirium prior to delirium onset."the research team opined.
Postoperative delirium is a frequent event after cardiac surgery. This meta-analysis aimed to identify relevant risk factors.For this meta-analysis, all original researches regarding patients undergoing mixed types of cardiac surgery (excluding transcatheter procedures) and postoperative delirium were evaluated for inclusion. On July 28th 2020, the research team searched PubMed, Embase, Web of Science and Scopus. Data about name of first author, year of publication, inclusion and exclusion criteria, research design, setting, method of delirium assessment, incidence of delirium, odds ratio (OR) and corresponding 95% confidence interval (CI) of risk factors, and other information relevant was collected. OR and 95% CI were used as metrics for summarized results. Random effects model was applied.
Data analysis highlighted some interesting facts.
Fourteen reports were included with a total sample size of 13,286. The incidence of delirium ranged from 4.1 to 54.9%.
Eight risk factors were identified including aging, diabetes, preoperative depression, mild cognitive impairment, carotid artery stenosis, NYHA functional class III or IV, time of mechanical ventilation and length of intensive care unit stay.
"We also noted these identified risk factors fell into four partly overlapping groups: risk factors associated with general condition such as age and diabetes; ischemic condition related risk factors such as carotid artery stenosis, NYHA III or IV and LVEF; cognition-related risk factors such as preoperative depression and mild cognitive impairment; and intervention related risk factors such as mechanical ventilation time and length of ICU stay. These features may enlighten future research in POD etiology. However, it is important to note that none of these identified risk factors can be declared to be causative at present since the mechanism and direct cause of POD remains to be determined."they concluded.
For full article follow the link: https://doi.org/10.1186/s13019-021-01496-w
Primary source: Journal of Cardiothoracic Surgery,BMJ