Strabismus and Refractive Error Study

Strabismus, the anomaly of ocular alignment, can involve either eye and can occur in any direction. They are classified according to the direction of deviation: inwards (esodeviations), outwards (exodeviations), and upwards or downwards (vertical deviations). Researches are gaining new momentum on decrypting the association of Strabismus with other ophthalmic causes.

According to a new study, refractive error is closely related to exodeviation and esodeviation. When managing refractive errors, these risk associations should be taken into account. This study was conducted by Si Hyung Lee and team with the objective to look into the relationship between refractive error and horizontal strabismus using data from a Korean population-based survey. The findings of this study were published in the Journal of American Association for Pediatric Ophthalmology and Strabismus.

The study included 22,887 people over the age of five who took part in the Korea National Health and Nutrition Examination Survey (KNHANES) between 2008 and 2011. Myopia, hyperopia, astigmatism, and anisometropia were the four types of refractive error. Multivariate logistic regression analysis was used to examine the relationship between refractive error and exodeviation or esodeviation.

Highlighted Findings of the Study

• After controlling for potential confounders, the analyses revealed an increased odds ratio (OR) for exodeviation with an increasing trend depending on myopia severity; moderate myopia, OR = 1.75; severe myopia, OR = 2.01.
• Exodeviation was not linked to hyperopia.
• Exodeviation was also found to be associated with astigmatism and anisometropia.

In conclusion, the authors said, "Refractive error was closely associated with exodeviation and esodeviation. These risk associations should be considered when managing refractive errors."

Reference

Lee, S. H., Jung, S. J., Ohn, Y.-H., & Chang, J. H. (2021). Association between refractive errors and horizontal strabismus: the Korea National Health and Nutrition Examination Survey. In Journal of American Association for Pediatric Ophthalmology and Strabismus. Elsevier BV. https://doi.org/10.1016/j.jaapos.2021.07.012