Medicine
Rapid High-Dose Buprenorphine Treatment Strategy Reduces Opioid Withdrawal In Individuals Using Fentanyl
Buprenorphine is a medication approved for pain and opioid dependence. New findings published in The American Journal on Addictions indicate that a transmucosal dose (which dissolves in the mouth) of buprenorphine followed by an injection of extended-release buprenorphine (BUP‐XR) may be an effective treatment for individuals with opioid use disorder who use fentanyl.
The results come from a recent secondary analysis of an open-label study in which 24 participants received a single 4 mg dose of transmucosal buprenorphine followed by an injection of 300 mg of BUP‐XR after approximately 1 hour.
Clinical Opioid Withdrawal Scale scores dropped significantly after treatment.
“Fentanyl and 20 other synthetic opioids are the leading cause of overdose deaths in 21 the United States and rapid induction to BUP‐XR injection may be an important potential treatment option for this at‐risk population,” the authors wrote.
Reference:
John J. Mariani, Robert L. Dobbins, Amy Heath, Frank Gray, Howard Hassman, Open-label investigation of rapid initiation of extended-release buprenorphine in patients using fentanyl and fentanyl analogs, https://doi.org/10.1111/ajad.13484.
Disclaimer: This website is designed for healthcare professionals and serves solely for informational purposes.
The content provided should not be interpreted as medical advice, diagnosis, treatment recommendations, prescriptions, or endorsements of specific medical practices. It is not a replacement for professional medical consultation or the expertise of a licensed healthcare provider.
Given the ever-evolving nature of medical science, we strive to keep our information accurate and up to date. However, we do not guarantee the completeness or accuracy of the content.
If you come across any inconsistencies, please reach out to us at
admin@doctornewsdaily.com.
We do not support or endorse medical opinions, treatments, or recommendations that contradict the advice of qualified healthcare professionals.
By using this website, you agree to our
Terms of Use,
Privacy Policy, and
Advertisement Policy.
For further details, please review our
Full Disclaimer.
0 Comments
Post a comment
No comments yet. Be the first to comment!