Psychological Impact Of Itchy Dermatoses: Study Highlights Link With Depression, Anxiety, And Stigmatization
- byDoctor News Daily Team
- 12 July, 2025
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A recent study led by Claudia Zeidler, MD, from the University Hospital Münster in Germany, sheds light on the psychological burden experienced by individuals with itchy dermatoses. The research explores the association between itch severity and feelings of depression, anxiety, and stigmatization, emphasizing the importance of addressing both the physical and psychological aspects of skin conditions.
While previous research has touched on the psychological impact of dermatoses, including itch-related stigmatization, this study delves deeper into the specific associations between itch severity and psychological distress. This study was published in the Journal Of The European Academy Of Dermatology and Venerology.
To investigate the relationship between itch severity and psychological variables such as stress, depression, anxiety, and stigmatization among individuals with various types of itchy dermatoses. The study utilized data from the ESDaP-study II, an observational, cross-sectional, multi-center study conducted across 17 European nations. Participants were recruited from dermatological outpatient clinics, and data collection included questionnaires assessing stress, stigmatization perceptions, depression, anxiety, and itch-related quality of life.
Key Findings:
• Substantial correlations were observed between itch severity and stress perceptions, particularly in individuals with rosacea.
• Patients with seborrheic dermatitis showed significant associations between itch intensity and reports of stigmatization, depression, and anxiety.
• Anxiety levels, gender, depression, and perceived stigmatization collectively influenced 9.3% of variation in itch intensity across the cohort.
• Females and individuals with heightened anxiety, depression, and perceived stigmatization reported stronger itch intensities.
The study underscores the psychological impact of itchy dermatoses, highlighting the need for integrated psychological interventions targeting both itch and related psychological variables. Healthcare providers should consider referring individuals with significant psychological distress for additional evaluation and support. These findings emphasize the importance of comprehensive care for patients with itchy skin conditions, addressing both physical and psychological aspects.
Reference:
Zeidler C, Kupfer J, Dalgard FJ, Bewley A, Evers AWM, Gieler U, et al. Dermatological patients with itch report more stress, stigmatization experience, anxiety and depression compared to patients without itch: Results from a European multi-centre study. J Eur Acad Dermatol Venereol. 2024; 00: 1–13. https://doi.org/10.1111/jdv.19913.
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