November 01, 2025

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Insomnia Associated Higher Central Sensitization Symptoms In TMD Patients

Insomnia and Central Sensitization in TMD Patients

Insomnia and Central Sensitization in TMD Patients

Insomnia is associated with higher scores of Central sensitization (CS) symptoms in patients with TMD suggests a new study published in The Journal of the American Dental Association.

Central sensitization (CS) and temporomandibular disorder (TMD) are both associated with insomnia. Therefore, the authors aimed to investigate whether insomnia was associated with more symptoms of CS in patients with TMD.

Study Overview

In 82 volunteers with TMD, insomnia was clinically assessed, allowing sample stratification according to its presence. The Central Sensitization Inventory questionnaire was self-applied to assess the clinical symptoms of CS.

Results

Participants with insomnia had significantly higher mean (SD) scores of CS according to the Central Sensitization Inventory than participants without insomnia. Insomnia was associated with higher scores of CS symptoms in patients with TMD.

Practical Implications

Insomnia influences TMD as well as its relationship with CS, and, therefore, it is critical to the clinical management of TMD.

Reference

Fernanda Grüninger Mercante, Giovana Fernandes, Guilherme Vinícius do Vale Braido, Monica Levy Andersen, Helena Hachul, Daniela Aparecida de Godoi Gonçalves. Insomnia is associated with symptoms of central sensitization in patients with painful temporomandibular disorders. The Journal of the American Dental Association. Published: April 20, 2023. DOI: https://doi.org/10.1016/j.adaj.2023.02.017

Keywords

  • Fernanda Grüninger Mercante
  • Giovana Fernandes
  • Guilherme Vinícius do Vale Braido
  • Monica Levy Andersen
  • Helena Hachul
  • Daniela Aparecida de Godoi Gonçalves
  • Insomnia
  • Associated
  • Symptoms
  • Central
  • Sensitization
  • Patients
  • Painful
  • Temporomandibular disorders
  • The Journal of the American Dental Association
  • Temporomandibular disorders
  • Insomnia
  • Pain modulation
  • Chronic pain
  • Sleep
  • Sleep disorders

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