Tissue engineering hybrid constructions with enhanced bone regeneration ability are emerging areas of development, suggests a study published in the Molecules.
After tooth loss, bone resorption is irreversible, leaving the area without the adequate bone volume for successful implant treatment. Bone grafting is the only solution to reverse dental bone loss and is a well-accepted procedure required in one in every four dental implants. A dental bone graft adds volume and density to your jaw in areas where bone loss has occurred. The bone graft material may be taken from your own body (autogenous), or it may be purchased from a human tissue bank (allograft) or an animal tissue bank (xenograft).
Research and development in materials, design and fabrication technologies have expanded over the years to achieve successful and long-lasting dental implants for tooth substitution.
If gum disease has damaged the bone surrounding your tooth root, your dentist might have to replace it with a graft. The bone graft can be made from small parts of your own bone, a synthetic bone, or donated bone. This procedure helps prevent tooth loss and may help promote natural bone regrowth.
This review critically presents the various dental bone graft and substitute materials that have been used to achieve a successful dental implant. The article also reviews the properties of dental bone grafts and various dental bone substitutes that have been studied or are currently available commercially. The various classifications of bone grafts and substitutes, including natural and synthetic materials, are critically presented, and available commercial products in each category are discussed. Different bone substitute materials, including metals, ceramics, polymers, or their combinations, and their chemical, physical, and biocompatibility properties are explored.
Thus, the researchers concluded that tissue engineering hybrid constructions with enhanced bone regeneration ability, such as cell-based or growth factor-based bone substitutes, are discussed as an emerging area of development.
Reference:
Bone Grafts and Substitutes in Dentistry: A Review of Current Trends and Developments by Rusin Zhao published in the Molecules
https://doi.org/10.3390/molecules26103007