November 04, 2025

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Adolescents With Autism Spectrum Disorder At Increased Risk For Periodontitis

People with autism spectrum disorder (ASD) may have poor oral health status because they often experience challenges with daily oral hygiene and have inadequate access to oral health care services.
Adolescents With Autism Spectrum Disorder Are at an Increased Risk for Periodontitis suggests a new study published in The Journal of the American Dental Association
The instant study explored periodontitis risk in adolescents with Autism Spectrum Disorder compared with those who did not have a diagnosis of ASD.

People with autism spectrum disorder (ASD) may have poor oral health status because they often experience challenges with daily oral hygiene and have inadequate access to oral health care services. This study explored periodontitis risk in adolescents with ASD compared with those who did not have a diagnosis of ASD.
Data from 2001 through December 31, 2011 from the Taiwan National Health Insurance Research Database on 3,473 adolescents with ASD and 34,730 age- and sex-matched people who did not have a diagnosis of ASD were obtained, and subsequent periodontitis was identified from enrollment through December 31, 2011.
Results
Adolescents with ASD (hazard ratio, 2.01; 95% CI, 1.84 to 2.20) were more likely to develop periodontitis at follow-up than those who did not have a diagnosis of ASD. Findings remained consistent in subanalyses stratified by sex and intellectual disability. People with ASD had periodontitis onset at an earlier mean (SD) age than those who did not have a diagnosis of ASD (17.97 [3.12] vs 21.86 [2.28] years; P < .001).
Autism Spectrum Disorder is an independent risk factor for subsequent periodontitis development. Oral health should be closely monitored in adolescents with ASD. Future investigation of the common pathogenesis between periodontitis and Autism Spectrum Disorder is warranted.
Reference:
Shih-Jen Tsai, Ju-Wei Hsu,Kai-Lin Huang, Tung-Ping Su, Tzeng-Ji Chen, Mu-Hong Chen. Autism spectrum disorder and periodontitis risk: A cohort study of 38,203 adolescents Published:April 25, 2023
DOI: https://doi.org/10.1016/j.adaj.2023.02.020

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